Ultimate Spider-Man is an animated TV series based on the superhero Spider-Man comics, published by Marvel Comics, including some elements of Marvel’s Ultimate line of books. S.H.I.E.L.D. Director Nick Fury offers Peter Parker the chance to raise his game to the next level, to become the Ultimate Spider-Man. Spidey takes on S.H.I.E.L.D. missions across the Marvel Universe, encounters new villains, and learn how to work with a team of four fellow teenage superheroes – Nova, White Tiger, Iron Fist, and Power Man. Influences from the Marvel live-action movies are also noticeable in this new Spiderman series.
During a sparring session with Spider-Man, Iron Fist is first attacked by a dark assassin and then suddenly called back to K’un-L’un, where he is to take up the mantle of the mystical city’s future king. Refusing to let his friend go like this, Spider-Man hitches a ride. When Iron Fist falls victim to the dark assassin’s poison attack, Spider-Man is chosen by his friend to go up against his competitor, the vicious and selfish Scorpion.
Using a Norn Stone, Loki shrinks Spider-Man’s team while looking for Thor. Nick Fury has Spider-Man’s team placed in the Helicarrier’s D.A.Y.C.A.R.E. area while S.H.I.E.L.D. continues to look for Thor. With Thor also having been shrunk, Spider-Man’s team must find a way to help Thor fight Loki and the Destroyer Armor and return to normal size.
A disgruntled Stark Industries scientist named Michael Tan develops and envelops himself in a swarm of self-replicating nanobots. Now Spider-Man must work with Iron Man to contain Swarm.
Spider-Man must face a bizarre threat when he travels to the Moon to rescue J. Jonah Jameson’s son.
Spider-Man’s team prepares to house a surprise party at Aunt May’s house. However, an attempt by Nova to shut down the secret S.H.I.E.L.D. security installations for some privacy makes the system go crazy, while Spider-Man must also come to terms with his teammates’ status as fellow houseboarders.